Majoie C B, Hulsmans F J, Castelijns J A, Sie L H, Walter A, Valk J, Albrecht K W
Department of Radiology, Academic Medical Center, University of Amsterdam, The Netherlands.
Neuroradiology. 1999 Feb;41(2):100-8. doi: 10.1007/s002340050713.
We reviewed the clinical and MRI findings in primary nerve-sheath tumours of the trigeminal nerve. We retrospectively reviewed the medical records, imaging and histological specimens of 10 patients with 11 primary tumours of the trigeminal nerve. We assessed whether tumour site, size, morphology or signal characteristics were related to symptoms and signs or histological findings. Histological proof was available for 8 of 11 tumours: six schwannomas and two plexiform neurofibromas. The other three tumours were thought to be schwannomas, because they were present in patients with neurofibromatosis type 2 and followed the course of the trigeminal nerve. Uncommon MRI appearances were observed in three schwannomas and included a large intratumoral haemorrhage, a mainly low-signal appearance on T2-weighted images and a rim-enhancing, multicystic appearance. Only four of nine schwannomas caused trigeminal nerve symptoms, including two with large cystic components, one haemorrhagic and one solid tumor. Of the five schwannomas which did not cause any trigeminal nerve symptoms, two were large. Only one of the plexiform neurofibromas caused trigeminal nerve symptoms. Additional neurological symptoms and signs, not related to the trigeminal nerve, could be attributed to the location of the tumour in three patients.
我们回顾了三叉神经原发性神经鞘瘤的临床和MRI表现。我们回顾性分析了10例患有11个三叉神经原发性肿瘤患者的病历、影像学和组织学标本。我们评估肿瘤部位、大小、形态或信号特征是否与症状体征或组织学表现相关。11个肿瘤中的8个有组织学证据：6个神经鞘瘤和2个丛状神经纤维瘤。另外3个肿瘤被认为是神经鞘瘤，因为它们出现在2型神经纤维瘤病患者中，并沿着三叉神经走行。在3个神经鞘瘤中观察到不常见的MRI表现，包括瘤内大量出血、T2加权像上主要呈低信号表现以及边缘强化的多囊性表现。9个神经鞘瘤中只有4个引起三叉神经症状，包括2个有大的囊性成分、1个出血性和1个实性肿瘤。在5个未引起任何三叉神经症状的神经鞘瘤中，2个较大。2个丛状神经纤维瘤中只有1个引起三叉神经症状。3例患者出现与三叉神经无关的其他神经症状和体征，可归因于肿瘤的位置。
