Maeshima E, Yamada Y, Kodama N, Mune M, Yukawa S
The Third Department of Internal Medicine, Wakayama Medical College, Wakayama City, Japan.
Scand J Rheumatol. 1999;28(1):54-7. doi: 10.1080/03009749950155797.
A 32-year-old woman diagnosed as systemic lupus erythematosus (SLE) became pregnant. During pregnancy she was treated with a daily dosage of prednisolone 15 mg. However, because the exanthema became worse, she was hospitalized on January 14, 1997 in order to receive immunoadsorption therapy. Before delivery we implemented the immunoadsorption therapy twice and cyclosporin A (CsA) was administered simultaneously. She gave birth in her 37th week. The baby weighed 2260 g at the time of delivery and had no deformities. The mother also had no side effects. The success of pregnancy and childbirth in our case, without any side effects, shows the possibility that the combination of CsA and immunoadsorption therapy may be considered safe to control a pregnancy complicated by SLE.
一名32岁被诊断为系统性红斑狼疮（SLE）的女性怀孕了。孕期她每日服用15毫克泼尼松龙进行治疗。然而，由于皮疹加重，她于1997年1月14日住院接受免疫吸附治疗。分娩前我们进行了两次免疫吸附治疗，并同时给予环孢素A（CsA）。她在孕37周时分娩。婴儿出生时体重2260克，无畸形。母亲也没有出现副作用。我们这个病例中妊娠和分娩成功且无任何副作用，表明CsA与免疫吸附治疗联合使用控制SLE合并妊娠可能是安全的。
