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结直肠癌筛查:现有方法及当前建议概述

Colorectal cancer screening: an overview of available methods and current recommendations.

作者信息

Early D S

机构信息

Department of Medicine, University of Missouri-Columbia, Ellis Fischel Cancer Center, 65203, USA.

出版信息

South Med J. 1999 Mar;92(3):258-65.

Abstract

BACKGROUND

Screening asymptomatic persons for colorectal cancer may decrease the incidence and mortality of this disease.

METHODS

The MEDLINE database was used to identify articles addressing the rationale for colorectal cancer screening, methods used and their effectiveness, and current recommendations.

RESULTS

Methods of screening for colorectal cancer include flexible sigmoidoscopy, fecal occult blood tests, barium enema, and colonoscopy. The method used and the frequency of screening are determined by assessing an individual's risk of having colorectal cancer.

CONCLUSIONS

Colorectal cancer is a common malignancy in the United States, is curable when detected at an early stage, and is potentially preventable. The acceptance of colorectal cancer screening by patients and physicians has been suboptimal. while there remains little debate about the potential for screening to reduce mortality from colorectal cancer, debate continues about the cost-effectiveness of colorectal cancer screening when applied to the general population.

摘要

背景

对无症状人群进行结直肠癌筛查可能会降低该疾病的发病率和死亡率。

方法

利用MEDLINE数据库识别阐述结直肠癌筛查基本原理、所采用的方法及其有效性以及当前建议的文章。

结果

结直肠癌的筛查方法包括乙状结肠镜检查、粪便潜血试验、钡剂灌肠和结肠镜检查。所采用的方法和筛查频率是通过评估个体患结直肠癌的风险来确定的。

结论

结直肠癌在美国是一种常见的恶性肿瘤,早期发现时可治愈,并且有可能预防。患者和医生对结直肠癌筛查的接受程度一直不理想。虽然对于筛查降低结直肠癌死亡率的可能性几乎没有争议,但对于将结直肠癌筛查应用于普通人群时的成本效益仍存在争议。

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