Bigler E D, Eidelberg E
Brain Res Bull. 1976 Sep-Oct;1(5):485-7. doi: 10.1016/0361-9230(76)90118-0.
The effect of metrazol on the capacity of dorsal lateral geniculate nucleus (dLGN) principal (P) cells to repetitively burst (after-discharge) following visual system stimulation was examined in P cells which differed in terms of response patterns to visual stimulation (latency of initial spike, extent of repetitive bursting, and on- or off-type responding cells). Twenty-seven P cells were examined in as many subjects. Metrazol augmented repetitive bursting irrespective of the type of P cell as long as repetitive bursting was present in the pre-metrazol period. P cells that displayed only a single initial burst to photic stimulation did not exhibit after-discharge bursting during the metrazol challenge. In all but one cell metrazol enhanced baseline firing rate. These results are discussed in terms of the putative nature of inhibition in the rat dLGN.
在对视刺激反应模式（初始峰电位潜伏期、重复爆发程度以及开型或关型反应细胞）不同的背外侧膝状核（dLGN）主（P）细胞中，研究了美解眠对视觉系统刺激后P细胞重复爆发（后放电）能力的影响。在同样数量的受试者中检查了27个P细胞。只要在使用美解眠前P细胞存在重复爆发，美解眠就会增强其重复爆发，而与P细胞类型无关。对光刺激仅表现出单次初始爆发的P细胞在美解眠激发期间未表现出后放电爆发。除一个细胞外，在所有细胞中美解眠均提高了基础放电率。根据大鼠dLGN中抑制作用的假定性质对这些结果进行了讨论。
