一项旨在确定胸腔镜检查期间湿化二氧化碳注入效果的随机对照试验。
A randomized controlled trial to determine the effects of humidified carbon dioxide insufflation during thoracoscopy.
作者信息
Mouton W G, Bessell J R, Pfitzner J, Dymock R B, Brealey J, Maddern G J
机构信息
University of Adelaide, Department of Surgery, The Queen Elizabeth Hospital, Woodville Road, Woodville, South Australia 5011, Australia.
出版信息
Surg Endosc. 1999 Apr;13(4):382-5. doi: 10.1007/s004649900994.
BACKGROUND
The humidification of gas insufflated during laparoscopy can reduce the degree of postoperative hypothermia and may result in less peritoneal reaction and less postoperative pain. The present study was designed to determine whether the beneficial effects of humidified gas insufflation also applied to thoracoscopy.
METHODS
Six pigs were each studied on three separate occasions with insufflation into the right thoracic cavity of either humidified gas, standard dry gas, or with no insufflation (control procedure). Core body temperature was recorded every 15 min, and biopsies of the parietal pleura were taken at the end of each study for electron microscopy.
RESULTS
Humidification of insufflated gas significantly minimized the fall in core temperature during the procedure. Electron microscopy showed that dry gas insufflation resulted in greater structural injury to the pleura than humidified gas insufflation.
CONCLUSIONS
The potential benefits of humidifying insufflation gas during thoracoscopy warrant its evaluation in the clinical setting.
背景
腹腔镜手术期间气体吹入的湿化可降低术后体温过低的程度，并可能导致较少的腹膜反应和术后疼痛。本研究旨在确定湿化气体吹入的有益效果是否也适用于胸腔镜检查。
方法
对6头猪分别进行3次独立研究，向右侧胸腔吹入湿化气体、标准干燥气体或不进行吹入（对照操作）。每15分钟记录一次核心体温，并在每次研究结束时取壁层胸膜活检组织用于电子显微镜检查。
结果
吹入气体的湿化显著减少了手术过程中核心体温的下降。电子显微镜检查显示，干燥气体吹入比湿化气体吹入对胸膜造成的结构损伤更大。
结论
胸腔镜检查期间湿化吹入气体的潜在益处值得在临床环境中进行评估。
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