Binda Maria Mercedes
Institut de Recherche Expérimentale et Clinique (IREC), Pôle de Gynécologie, Avenue Mounier 52, bte B1.52.02, 1200, Brussels, Belgium.
Arch Gynecol Obstet. 2015 Nov;292(5):955-71. doi: 10.1007/s00404-015-3717-y. Epub 2015 Apr 25.
The peritoneum is the serous membrane that covers the abdominal cavity and most of the intra-abdominal organs. It is a very delicate layer highly susceptible to damage and it is not designed to cope with variable conditions such as the dry and cold carbon dioxide (CO2) during laparoscopic surgery. The aim of this review was to evaluate the effects caused by insufflating dry and cold gas into the abdominal cavity after laparoscopic surgery.
A literature search using the Pubmed was carried out. Articles identified focused on the key issues of laparoscopy, peritoneum, morphology, pneumoperitoneum, humidity, body temperature, pain, recovery time, post-operative adhesions and lens fogging.
Insufflating dry and cold CO2 into the abdomen causes peritoneal damage, post-operative pain, hypothermia and post-operative adhesions. Using humidified and warm gas prevents pain after surgery. With regard to hypothermia due to desiccation, it can be fully prevented using humidified and warm gas. Results relating to the patient recovery are still controversial.
The use of humidified and warm insufflation gas offers a significant clinical benefit to the patient, creating a more physiologic peritoneal environment and reducing the post-operative pain and hypothermia. In animal models, although humidified and warm gas reduces post-operative adhesions, humidified gas at 32 °C reduced them even more. It is clear that humidified gas should be used during laparoscopic surgery; however, a question remains unanswered: to achieve even greater clinical benefit to the patient, at what temperature should the humidified gas be when insufflated into the abdomen? More clinical trials should be performed to resolve this query.
腹膜是覆盖腹腔和大多数腹腔内器官的浆膜。它是一层非常脆弱的组织,极易受损,且无法应对诸如腹腔镜手术中干燥寒冷的二氧化碳(CO2)等多变状况。本综述的目的是评估腹腔镜手术后向腹腔内注入干燥寒冷气体所产生的影响。
利用PubMed进行文献检索。所检索到的文章聚焦于腹腔镜检查、腹膜、形态学、气腹、湿度、体温、疼痛、恢复时间、术后粘连和镜头起雾等关键问题。
向腹腔内注入干燥寒冷的CO2会导致腹膜损伤、术后疼痛、体温过低和术后粘连。使用加湿温暖的气体可预防术后疼痛。对于因干燥引起的体温过低,使用加湿温暖的气体可完全预防。关于患者恢复的结果仍存在争议。
使用加湿温暖的充气气体对患者具有显著的临床益处,可营造更接近生理状态的腹膜环境,减轻术后疼痛和体温过低。在动物模型中,尽管加湿温暖的气体可减少术后粘连,但32°C的加湿气体能更有效地减少粘连。显然,腹腔镜手术期间应使用加湿气体;然而,一个问题仍未得到解答:为给患者带来更大的临床益处,向腹腔内充气时加湿气体的温度应为多少?需要进行更多的临床试验来解决这一疑问。