灰葡萄孢对抑菌倍半萜广藿香醇的生物转化
Biotransformation of the fungistatic sesquiterpenoid patchoulol by botrytis cinerea.
作者信息
Aleu J, Hanson JR, Galan RH, Collado IG
机构信息
Departamento de Quimica Organica, Facultad de Ciencias, Universidad de Cadiz, Apdo. 40, 11510 Puerto Real, Cadiz, Spain, and The School of Chemistry, Physics and Enviromental Science, University of Sussex, Brighton, Sussex BN1 9QJ.
出版信息
J Nat Prod. 1999 Mar;62(3):437-40. doi: 10.1021/np980416e.
PMID:10096853
Abstract
Biotransformation of the fungistatic sesquiterpenoid patchoulol (1) by the fungus Botrytis cinerea affords the 5-, 7- and (8R)-hydroxy (2, 3, and 5) derivatives as the major metabolites, together with a number of minor metabolites (4, 6-9) arising from hydroxylation at C-2, C-3, C-5, C-9, C-13, and C-14.
摘要
真菌灰葡萄孢对抑菌倍半萜广藿香醇（1）进行生物转化，生成5-、7-和（8R）-羟基（2、3和5）衍生物作为主要代谢产物，同时还产生了一些由C-2、C-3、C-5、C-9、C-13和C-14羟基化产生的次要代谢产物（4、6-9）。
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