Sims D N, James R, Christensen T
Forensic Science Centre, Adelaide, Australia.
J Forensic Sci. 1999 Mar;44(2):447-9.
Deaths attributed to ingestion of Nicotiana glauca are extremely rare. We report here a case where a 43-year-old man was found dead after apparently drinking a water extract of Nicotiana glauca. The primary alkaloid in the plant is anabasine. Toxicological analysis by capillary gas chromatography showed the deceased had a blood anabasine concentration of 2.2 mg/L. Clinically, the features of poisoning are nicotine-like and if death occurs it results from respiratory paralysis. The case further supports the view that, in the human, anabasine is considerably more toxic than nicotine.
因摄入黄花烟草而导致的死亡极为罕见。我们在此报告一例，一名43岁男子在明显饮用了黄花烟草的水提取物后被发现死亡。该植物中的主要生物碱是新烟草碱。毛细管气相色谱法进行的毒理学分析显示，死者血液中新烟草碱浓度为2.2毫克/升。临床上，中毒特征与尼古丁相似，若发生死亡则是由呼吸麻痹所致。该病例进一步支持了这样一种观点，即对人类而言，新烟草碱的毒性远大于尼古丁。
