Wändell P E, Brorsson B, Aberg H
Department of Clinical Neuroscience and Family Medicine, Karolinska Institutet, Stockholm, Sweden.
Qual Life Res. 1998 Dec;7(8):751-60. doi: 10.1023/a:1008893121086.
To assess change over time in health-related quality of life (HRQoL) in diabetic patients in primary health care and differences to general Swedish population samples, 341 diabetic subjects in 1992 and 413 in 1995, aged 20-84 years, were chosen from three community health centres (CHCs) in the Metropolitan Stockholm area and compared to controls matched by age and sex in randomly selected samples of 2,366 subjects in 1991 and 2,500 in 1995 from the general population. HRQoL was assessed by the Swedish Health-Related Quality of Life Survey (SWED-QUAL), adapted from the Medical Outcomes Study, which measures aspects of physical, mental, social and general health in 13 scales. Information on diabetic and general medical data were extracted from the medical records at the CHCs. HRQoL was lower in diabetic subjects compared with the general population in both 1992 and 1995 in all scales except family functioning and marital functioning. The level of HRQoL did not change significantly between the diabetic samples, but decreased in the population samples, making the difference compared to diabetic patients smaller in five of the scales. The most significant predicting factors for the SWED-QUAL results in diabetic patients in 1995 were the vascular and non-vascular co-morbidity.
为评估初级卫生保健中糖尿病患者健康相关生活质量(HRQoL)随时间的变化以及与瑞典普通人群样本的差异,从斯德哥尔摩大区的三个社区卫生中心(CHC)选取了1992年的341名糖尿病患者和1995年的413名糖尿病患者,年龄在20 - 84岁之间,并与1991年随机抽取的2366名和1995年随机抽取的2500名来自普通人群的年龄和性别匹配的对照组进行比较。HRQoL通过瑞典健康相关生活质量调查(SWED-QUAL)进行评估,该调查改编自医学结局研究,通过13个量表来衡量身体、心理、社会和总体健康方面。糖尿病和一般医疗数据信息从社区卫生中心的医疗记录中提取。在1992年和1995年,除家庭功能和婚姻功能外,糖尿病患者在所有量表中的HRQoL均低于普通人群。糖尿病样本之间的HRQoL水平没有显著变化,但人群样本中的HRQoL有所下降,使得在五个量表中与糖尿病患者的差异变小。1995年糖尿病患者SWED-QUAL结果的最显著预测因素是血管性和非血管性合并症。