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经皮硝酸甘油治疗勃起功能障碍:一项安慰剂对照临床试验。

Transcutaneous nitroglycerine in the treatment of erectile dysfunction: a placebo controlled clinical trial.

作者信息

Gramkow J, Lendorf A, Zhu J, Meyhoff H H

机构信息

Department of Surgery, Hilleroed Hospital, Denmark.

出版信息

Int J Impot Res. 1999 Feb;11(1):35-9. doi: 10.1038/sj.ijir.3900380.

DOI:10.1038/sj.ijir.3900380
PMID:10098952
Abstract

Transcutaneous nitroglycerine has previously been reported to be effective in the treatment of erectile dysfunction. We present our results with the drug in a randomised, placebo controlled, double-blind crossover study. The effect of the drug has been evaluated both under laboratory conditions and in a home study. Eighteen men were included in the study. No effect of nitroglycerine could be demonstrated under laboratory conditions by application of the Rigiscan Monitor. In the home study there was no statistical significant effect of transcutaneous nitroglycerine compared to placebo (P= 0.2813).

摘要

经皮硝酸甘油此前已被报道可有效治疗勃起功能障碍。我们在一项随机、安慰剂对照、双盲交叉研究中展示了该药物的研究结果。已在实验室条件下和家庭研究中对该药物的效果进行了评估。18名男性参与了该研究。通过使用Rigiscan监测仪,在实验室条件下未证实硝酸甘油有效果。在家庭研究中,与安慰剂相比,经皮硝酸甘油没有统计学上的显著效果(P = 0.2813)。

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