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经皮硝酸甘油对阳痿的非侵入性治疗

Non-invasive management of impotence with transcutaneous nitroglycerin.

作者信息

Meyhoff H H, Rosenkilde P, Bødker A

机构信息

Department of Urology, Glostrup Hospital, University of Copenhagen, Denmark.

出版信息

Br J Urol. 1992 Jan;69(1):88-90. doi: 10.1111/j.1464-410x.1992.tb15466.x.

DOI:10.1111/j.1464-410x.1992.tb15466.x
PMID:1737261
Abstract

Nitroglycerin plasters were applied to the penis in 10 impotent men and the erectile effect assessed. During laboratory testing all patients achieved an erectile response. Self-administration of nitroglycerin patches restored potency in 4 patients and was preferred to papaverine auto-injection by 3. Headache was a common side effect during initial administration. An attempt to treat impotence with nitroglycerin plaster seems worthwhile before starting extensive investigations or invasive treatment.

摘要

对10名阳痿男性在阴茎上涂抹硝酸甘油贴剂,并评估勃起效果。在实验室测试期间,所有患者都出现了勃起反应。4名患者通过自行使用硝酸甘油贴片恢复了性功能,且有3名患者更倾向于使用硝酸甘油贴片而非罂粟碱自我注射。初始给药期间,头痛是常见的副作用。在开始广泛的检查或侵入性治疗之前,尝试用硝酸甘油贴剂治疗阳痿似乎是值得的。

相似文献

1
Non-invasive management of impotence with transcutaneous nitroglycerin.经皮硝酸甘油对阳痿的非侵入性治疗
Br J Urol. 1992 Jan;69(1):88-90. doi: 10.1111/j.1464-410x.1992.tb15466.x.
2
Transcutaneous nitroglycerin therapy in the treatment of impotence.经皮硝酸甘油疗法治疗阳痿。
Urol Int. 1989;44(5):309-12. doi: 10.1159/000281528.
3
Nitroglycerin ointment in the treatment of impotence.硝酸甘油软膏治疗阳痿。
J Urol. 1993 Oct;150(4):1241-3. doi: 10.1016/s0022-5347(17)35742-7.
4
Transcutaneous nitroglycerin in the treatment of erectile dysfunction in spinal cord injured.
Paraplegia. 1992 Aug;30(8):554-7. doi: 10.1038/sc.1992.114.
5
Minoxidil versus nitroglycerin: a prospective double-blind controlled trial in transcutaneous erection facilitation for organic impotence.米诺地尔与硝酸甘油对比:一项用于促进器质性阳痿经皮勃起的前瞻性双盲对照试验。
J Urol. 1991 Jul;146(1):50-3. doi: 10.1016/s0022-5347(17)37712-1.
6
Transcutaneous nitroglycerine in the treatment of erectile dysfunction: a placebo controlled clinical trial.经皮硝酸甘油治疗勃起功能障碍:一项安慰剂对照临床试验。
Int J Impot Res. 1999 Feb;11(1):35-9. doi: 10.1038/sj.ijir.3900380.
7
Topical nitroglycerin: a potential treatment for impotence.局部用硝酸甘油:一种治疗阳痿的潜在方法。
J Urol. 1989 Mar;141(3):546-8. doi: 10.1016/s0022-5347(17)40888-3.
8
Comparison of transdermal nitroglycerin and intracavernous injection of papaverine in the treatment of erectile dysfunction in patients with spinal cord lesions.
Spinal Cord. 1997 Feb;35(2):99-103. doi: 10.1038/sj.sc.3100361.
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[Dionysos plaster or gunpowder without bullets].[酒神狄俄尼索斯膏药或无子弹的火药]
Ugeskr Laeger. 2008 Apr 14;170(16):1375; author reply 1375.
10
Re: Topical nitroglycerin: a potential treatment for impotence.关于:局部用硝酸甘油:一种治疗阳痿的潜在方法。
J Urol. 1990 Mar;143(3):586. doi: 10.1016/s0022-5347(17)40030-9.

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J Pharm Sci. 2013 Sep;102(9):3070-81. doi: 10.1002/jps.23550. Epub 2013 May 13.
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An overview of the diagnosis and treatment of erectile dysfunction.勃起功能障碍的诊断与治疗概述
Drugs. 2006;66(18):2339-55. doi: 10.2165/00003495-200666180-00006.
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A comparative review of the options for treatment of erectile dysfunction: which treatment for which patient?
勃起功能障碍治疗方案的比较性综述:何种治疗适用于何种患者?
Drugs. 2005;65(12):1621-50. doi: 10.2165/00003495-200565120-00003.
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Topical agents and erectile dysfunction: is there a place?
Curr Urol Rep. 2002 Dec;3(6):471-6. doi: 10.1007/s11934-002-0100-x.
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Comparative tolerability and efficacy of treatments for impotence.阳痿治疗方法的耐受性和疗效比较
Drug Saf. 1999 Feb;20(2):133-46. doi: 10.2165/00002018-199920020-00004.
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Topical treatment of erectile dysfunction: randomised double blind placebo controlled trial of cream containing aminophylline, isosorbide dinitrate, and co-dergocrine mesylate.勃起功能障碍的局部治疗:含氨茶碱、硝酸异山梨酯和甲磺酸麦角隐亭的乳膏的随机双盲安慰剂对照试验
BMJ. 1996 Jun 15;312(7045):1512-5. doi: 10.1136/bmj.312.7045.1512.
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Regulation of tone in penile cavernous smooth muscle. Established concepts and new findings.阴茎海绵体平滑肌张力的调节。既定概念与新发现。
World J Urol. 1994;12(5):249-61. doi: 10.1007/BF00191204.
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Nitric oxide--from mediator to medicines.一氧化氮——从介质到药物
J R Coll Physicians Lond. 1994 May-Jun;28(3):209-19.