Foote K D, Friedman W A, Buatti J M, Bova F J, Meeks S A
Department of Neurological Surgery, University of Florida, Gainesville, Florida 32610, USA.
Neurosurg Clin N Am. 1999 Apr;10(2):203-42.
This article begins with a brief introduction to the concepts and techniques of linear accelerator-based stereotactic radiosurgery. The expanding role of radiosurgery in the treatment of brain tumors is explored in depth, including detailed discussions of the five intracranial neoplasms most frequently treated with radiosurgery. These include both benign (i.e., vestibular schwannoma, meningioma, pituitary adenoma) and malignant (i.e., cerebral metastasis, malignant glioma) pathologies. For each of these, a thorough review of published radiosurgical results is presented along with a discussion of common treatment modalities. The role of radiosurgery in the treatment of brain tumors continues to be defined, but an effort is made to provide reasonable indications for and against radiosurgery based on the current state of the art.
本文首先简要介绍基于直线加速器的立体定向放射外科的概念和技术。深入探讨了放射外科在脑肿瘤治疗中不断扩大的作用，包括对最常接受放射外科治疗的五种颅内肿瘤的详细讨论。这些肿瘤包括良性（即前庭神经鞘瘤、脑膜瘤、垂体腺瘤）和恶性（即脑转移瘤、恶性胶质瘤）病变。对于每种肿瘤，本文都对已发表的放射外科治疗结果进行了全面综述，并讨论了常见的治疗方式。放射外科在脑肿瘤治疗中的作用仍在不断明确，但本文基于当前的技术水平，努力提供支持和反对放射外科治疗的合理指征。
