Harsh G, Loeffler J S, Thornton A, Smith A, Bussiere M, Chapman P H
Northeast Proton Therapy Center, Department of Neurosurgery and Radiation Oncology, Harvard Medical School, Boston, Massachusetts, USA.
Neurosurg Clin N Am. 1999 Apr;10(2):243-56.
The technique of stereotactic proton radiosurgery is discussed in depth in this article. The physics of the proton beam in radiosurgery is explained, and the different factors of beam delivery are examined. These key factors (correspondence to shape, accuracy of delineation of volume, correspondence to volume, and accuracy of delivery vary) with each of the radiosurgical techniques, from Gamma Knife surgery to linear accelerator therapy. Clinical series in the use of proton radiosurgery are also presented, with an emphasis on efficacy and uses.
本文深入讨论了立体定向质子放射外科技术。解释了放射外科中质子束的物理原理,并研究了束流传输的不同因素。从伽玛刀手术到直线加速器治疗,这些关键因素(与形状的对应性、体积勾画的准确性、与体积的对应性以及传输的准确性各不相同)因每种放射外科技术而异。文中还介绍了质子放射外科的临床应用系列,重点强调了疗效和用途。