Abignente E, Arena F, De Caprariis P
Farmaco Sci. 1976 Nov;31(11):776-84.
A group of ethyl imidazo (1,2-a) and imidazo (1,2-c)pyrimidin-2-acetates was prepared, starting respectively from 2-amino- and 4-aminopyrimidines, by reaction with ethyl 4-bromoacetoacetate. From these esters the corresponding acids were prepared and their antiinflammatory activity was evaluated.
以2-氨基嘧啶和4-氨基嘧啶分别为原料，与4-溴乙酰乙酸乙酯反应，制备了一组乙基咪唑并(1,2 - a)和咪唑并(1,2 - c)嘧啶-2-乙酸酯。由这些酯制备了相应的酸，并对其抗炎活性进行了评估。
