Abignente E, Arena F, De Caprariis P
Farmaco Sci. 1976 Dec;31(12):880-7.
We have prepared a group of ethyl imidazo [2,1-b]thiazole-6- and imidazo[2,1-b]benzothiazole-2-acetates, starting from some substituted 2-aminothiazoles and 2-aminobenzothiazoles, by reaction with ethyl 4-bromoacetoacetate. From these esters we have obtained the corresponding acetic acids, and we have tested their anti-inflammatory activity.
我们从一些取代的2-氨基噻唑和2-氨基苯并噻唑出发，通过与4-溴乙酰乙酸乙酯反应，制备了一组咪唑并[2,1-b]噻唑-6-乙酸乙酯和咪唑并[2,1-b]苯并噻唑-2-乙酸乙酯。从这些酯类化合物中我们得到了相应的乙酸，并测试了它们的抗炎活性。
