Synthesis and pharmacological properties of some new 1,1-diarylacetic acid derivatives.
作者信息
Jawdosiuk M, Ludwikow M, Makosza M, Ernest K, Przemyk B, Bogdal M, Kierylowicz H
出版信息
Farmaco Sci. 1976 Sep;31(9):671-80.
PMID:1010039
Abstract
A series of 13 new 1,1-diphenylacetic acid derivatives was synthesized via common transformations of 2-phenyl-2-(p-nitrophenyl) propio- and butyronitriles. The compounds were submitted to pharmacological screening. 2-Phenyl-2-(p-aminophenyl)propionamide (VIII) showed high anticonvulsant activity.
摘要
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