白细胞增多和中性粒细胞增多犬的临床结局及相关疾病：118例病例（1996 - 1998年）
Clinical outcome and associated diseases in dogs with leukocytosis and neutrophilia: 118 cases (1996-1998).
作者信息
Lucroy M D, Madewell B R
机构信息
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616, USA.
出版信息
J Am Vet Med Assoc. 1999 Mar 15;214(6):805-7.
OBJECTIVE
To describe diseases, prognosis, and clinical outcomes associated with leukocytosis and neutrophilia in dogs.
DESIGN
Retrospective study.
ANIMALS
118 dogs with leukocytosis and neutrophilia.
PROCEDURE
Medical records from 1996 to 1998 were examined for dogs with WBC > or = 50,000 cells/microliter and neutrophilia > or = 50%. Signalment, absolute and differential WBC counts, body temperature, clinical or pathologic diagnosis, duration and cost of hospitalization, and survival time were reviewed.
RESULTS
Mean age was 7.7 years, WBC count was 65,795 cells/microliter, and absolute neutrophil count was 53,798 cells/microliter. Mean duration of hospitalization was 7.4 days and cost of hospitalization was $2,028.00. Forty (34%) dogs were febrile, and 73 (62%) dogs died. Overall median survival time was 17 days. Dogs with neoplasia or fever were more likely to die than dogs that were hospitalized or had systemic or local infections.
CLINICAL IMPLICATIONS
Leukocytosis and neutrophilia were associated with high mortality rate and have prognostic value. Given the mean duration and cost of hospitalization, frank discussion with an owner at first recognition of leukocytosis and neutrophilia may be warranted.
目的
描述与犬白细胞增多和中性粒细胞增多相关的疾病、预后及临床结局。
设计
回顾性研究。
动物
118只患有白细胞增多和中性粒细胞增多的犬。
方法
检查1996年至1998年白细胞计数≥50,000个/微升且中性粒细胞比例≥50%的犬的病历。回顾品种、白细胞总数及分类计数、体温、临床或病理诊断、住院时间及费用以及生存时间。
结果
平均年龄7.7岁，白细胞计数为65,795个/微升，绝对中性粒细胞计数为53,798个/微升。平均住院时间为7.4天，住院费用为2,028.00美元。40只（34%）犬发热，73只（62%）犬死亡。总体中位生存时间为17天。患有肿瘤或发热的犬比住院或患有全身或局部感染的犬死亡可能性更大。
临床意义
白细胞增多和中性粒细胞增多与高死亡率相关且具有预后价值。鉴于平均住院时间和费用，在首次发现白细胞增多和中性粒细胞增多时与犬主人进行坦诚讨论可能是必要的。
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