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猫极端嗜中性白细胞增多症相关的临床结局和疾病:104例病例(1991 - 1999年)

Clinical outcome and diseases associated with extreme neutrophilic leukocytosis in cats: 104 cases (1991-1999).

作者信息

Lucroy M D, Madewell B R

机构信息

Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616, USA.

出版信息

J Am Vet Med Assoc. 2001 Mar 1;218(5):736-9. doi: 10.2460/javma.2001.218.736.

DOI:10.2460/javma.2001.218.736
PMID:11280408
Abstract

OBJECTIVE

To describe diseases, prognosis, and clinical outcomes associated with extreme neutrophilic leukocytosis in cats.

DESIGN

Retrospective study.

ANIMALS

104 cats with extreme neutrophilic leukocytosis.

PROCEDURE

Medical records from 1991 to 1999 were examined to identify cats that had > or =50,000 WBC/microl with > or =50% neutrophils. Signalment, absolute and differential WBC counts, rectal temperature, clinical or pathologic diagnosis, duration and cost of hospitalization, and survival time were reviewed.

RESULTS

Mean age of cats was 8.3 years, mean WBC count was 73,055 cells/microl, and mean absolute neutrophil count was 59,046 cells/microl. Mean duration of hospitalization was 5.9 days, and mean cost of hospitalization was $2,010. Twenty-nine (28%) cats were febrile, and 63 (61%) cats died. Overall median survival time was 30 days. Cats with neoplasia were nearly 14 times as likely to die unexpectedly as cats with other diseases.

CONCLUSIONS AND CLINICAL RELEVANCE

Extreme neutrophilic leukocytosis was associated with a high mortality rate. The prognostic importance of extreme neutrophilic leukocytosis should not be overlooked. Cats and dogs have similar diseases, mortality rates, and treatment costs associated with extreme neutrophilic leukocytosis.

摘要

目的

描述与猫极端嗜中性白细胞增多症相关的疾病、预后及临床结局。

设计

回顾性研究。

动物

104只患有极端嗜中性白细胞增多症的猫。

步骤

检查1991年至1999年的病历,以确定白细胞计数≥50,000/微升且嗜中性粒细胞≥50%的猫。回顾动物特征、白细胞绝对计数及分类计数、直肠温度、临床或病理诊断、住院时间及费用以及生存时间。

结果

猫的平均年龄为8.3岁,平均白细胞计数为73,055个/微升,平均嗜中性粒细胞绝对计数为59,046个/微升。平均住院时间为5.9天,平均住院费用为2010美元。29只(28%)猫发热,63只(61%)猫死亡。总体中位生存时间为30天。患有肿瘤的猫意外死亡的可能性是患有其他疾病猫的近14倍。

结论及临床意义

极端嗜中性白细胞增多症与高死亡率相关。极端嗜中性白细胞增多症的预后重要性不应被忽视。猫和狗在与极端嗜中性白细胞增多症相关的疾病、死亡率及治疗费用方面相似。

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