整合子介导的铜绿假单胞菌对利福平的耐药性
Integron-mediated rifampin resistance in Pseudomonas aeruginosa.
作者信息
Tribuddharat C, Fennewald M
机构信息
Department of Microbiology and Immunology, Finch University of the Health Sciences, Chicago Medical School, Illinois 60064, USA.
出版信息
Antimicrob Agents Chemother. 1999 Apr;43(4):960-2. doi: 10.1128/AAC.43.4.960.
Abstract
A new rifampin resistance gene, arr-2, has been found in Pseudomonas aeruginosa. The ARR-2 protein shows 54% amino acid identity to the rifampin ADP-ribosylating transferase encoded by the arr gene from Mycobacterium smegmatis. This arr-2 gene is located on a gene cassette within a class I integron.
摘要
在铜绿假单胞菌中发现了一种新的利福平抗性基因arr-2。ARR-2蛋白与耻垢分枝杆菌arr基因编码的利福平ADP-核糖基转移酶的氨基酸同一性为54%。该arr-2基因位于Ⅰ类整合子内的一个基因盒上。
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