Recchia G D, Hall R M
Dept of Biochemistry, University of Oxford, UK.
Trends Microbiol. 1997 Oct;5(10):389-94. doi: 10.1016/S0966-842X(97)01123-2.
Many of the acquired antibiotic resistance genes found in enterobacteria and pseudomonads are part of small mobile elements known as gene cassettes, and other genes are also likely to be found in cassettes. The origins of the genes and the recombination sites that make up cassettes are not known, but recent analyses of available data suggest that cassettes may be ancient structures, and some hypotheses for how they are formed can now be examined.
在肠杆菌和假单胞菌中发现的许多获得性抗生素抗性基因是称为基因盒的小移动元件的一部分，其他基因也可能存在于基因盒中。构成基因盒的基因起源和重组位点尚不清楚，但最近对现有数据的分析表明，基因盒可能是古老的结构，现在可以研究一些关于它们如何形成的假说。
