St John R K
J Am Vener Dis Assoc. 1976 Dec;3(2 Pt 2):146-7.
The English literature on the treatment of late benign syphilis with penicillin was reviewed. To date there have been no controlled randomized therapeutic trials to support the efficacy of this therapy. This disease responds rapidly to all antisyphilitic drugs including arsphenamine and heavy metals. There are ample case reports and 2 major therapy studies which demonstrate the safety and beneficial effects of penicillin in individual patients. Although the exact dosage and duration of therapy are open to speculation, it is wise to treat patients with late benign syphilis with doses of penicillin judged to be effective for concomitant neuro-or cardiovascular syphilis.
对关于用青霉素治疗晚期良性梅毒的英文文献进行了综述。迄今为止，尚无对照随机治疗试验来支持这种疗法的疗效。这种疾病对包括胂凡纳明和重金属在内的所有抗梅毒药物反应迅速。有大量病例报告以及两项主要治疗研究证明了青霉素对个别患者的安全性和有益效果。尽管确切的治疗剂量和疗程尚有待推测，但用判定对并发神经梅毒或心血管梅毒有效的青霉素剂量来治疗晚期良性梅毒患者是明智的。
