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食品和药物成分的热解气相色谱鉴定。II. 青霉素和头孢菌素的定性和定量分析。

Pyrolysis GLC identification of food and drug ingredients. II. Qualitative and quantitative analysis of penicillins and cephalosporins.

作者信息

Roy T A, Szinal S S

出版信息

J Chromatogr Sci. 1976 Dec;14(12):580-4. doi: 10.1093/chromsci/14.12.580.

DOI:10.1093/chromsci/14.12.580
PMID:1010867
Abstract

Pyrolysis gas-liquid chromatography (PGLC) provided reproducible pyrograms for 14 penicillins and cephalosporins studied which permitted direct characterization and differentiation of the antibiotics in almost all cases. The quantitative application of the technique was explored using four of the antibiotics. Standard curves were constructed based on the height of the most intense (and symmetrical) peak in the pyrograms. Excellent linearity was obtained in the ranges studied, 10 nanograms - 100 micrograms. Further quantitative application of the method is discussed.

摘要

热解气相色谱法（PGLC）为所研究的14种青霉素和头孢菌素提供了可重现的热解图，几乎在所有情况下都能直接对抗生素进行表征和鉴别。使用其中四种抗生素探索了该技术的定量应用。基于热解图中最强烈（且对称）峰的高度构建了标准曲线。在所研究的10纳克至100微克范围内获得了出色的线性关系。还讨论了该方法的进一步定量应用。

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