Cabral R J, King T T, Scott D F
J Neurol Neurosurg Psychiatry. 1976 Nov;39(11):1052-6. doi: 10.1136/jnnp.39.11.1052.
One-hundred-and-fifty-two patients who underwent surgery for intracranial aneurysm were studied to determine the incidence of postoperative epilepsy in relation to the site of the aneurysm and the type of surgical approach. The overall incidence of epilepsy was 22%. Of the 116 patients treated by the intracranial approach 27.5% developed epilepsy, in contrast with only 5% of the 36 patients who had carotid artery ligation in the neck. Epilepsy occurred most frequently (35%) with middle cerebral artery aneurysms, especially if moderate or severe operative trauma was sustained and there was postoperative dysphasia.
对152例接受颅内动脉瘤手术的患者进行了研究,以确定术后癫痫的发生率与动脉瘤部位及手术方式的关系。癫痫的总体发生率为22%。采用颅内手术方式治疗的116例患者中,27.5%发生了癫痫,相比之下,颈部进行颈动脉结扎的36例患者中只有5%发生癫痫。癫痫最常发生于大脑中动脉动脉瘤(发生率为35%),尤其是在遭受中度或重度手术创伤且术后出现吞咽困难的情况下。