小鼠胎儿血红蛋白

Mouse fetal hemoglobin.

作者信息

Wu N C, Sikkema D A, Zucker R M

出版信息

Biochim Biophys Acta. 1978 Sep 26;536(1):306-11. doi: 10.1016/0005-2795(78)90078-8.

Abstract

Using isoelectric focusing, a fetal hemoglobin was found in the peripheral blood of C57BL/6 fetal mouse during the 14 to 20 days gestational period. In acid-urea polyacrylamide gel the pattern of this fetal hemoglobin was different from that of the adult hemoglobin. The mouse fetal hemoglobin was differentiated from the mouse adult hemoglobin by immunodiffusion reaction. It suggests that there is a transient fetal hemoglobin in the C57BL/6 mouse during gestational age.

摘要

通过等电聚焦法，在妊娠14至20天的C57BL/6胎鼠外周血中发现了一种胎儿血红蛋白。在酸性尿素聚丙烯酰胺凝胶中，这种胎儿血红蛋白的图谱与成年血红蛋白不同。通过免疫扩散反应可将小鼠胎儿血红蛋白与成年血红蛋白区分开来。这表明在C57BL/6小鼠的胎龄期存在一种短暂的胎儿血红蛋白。