Vallotton M B
Schweiz Med Wochenschr. 1976 Dec 11;106(50):1766-72.
Maintenance of normotension rests upon the overall salt and water balance, which, in the event of disequilibrium, modifies body fluid, cardiac output and total peripheral resistance. The kidneys play a central role in this hydro-saline regulation. The central and autonomous nervous systems, the renin-angiotensin system, the mineralocorticoids, the antidiuretic hormone and the kallikrein-bradykinin-prostaglandin system all affect this regulation and are closely interrelated. The role of each of these nervous and endocrine systems in hypertension, and their close interrelationship, is briefly reviewed.
血压正常的维持取决于整体的盐和水平衡，一旦失衡，就会改变体液、心输出量和总外周阻力。肾脏在这种水盐调节中起核心作用。中枢神经系统和自主神经系统、肾素 - 血管紧张素系统、盐皮质激素、抗利尿激素以及激肽释放酶 - 缓激肽 - 前列腺素系统均影响这种调节，且相互密切关联。本文简要综述了这些神经和内分泌系统在高血压中的作用及其密切的相互关系。
