Uromucoid in the rat: its isolation, localization in the kidney and concentration in the urine.

Based on the finding that rat uromucoid cross reacts with antihuman uromucoid, rat uromucoid was isolated by means of immune absorption chromatography. Using a monospecific antiserum obtained with the use of this preparation, uromucoid was shown to be present in the distal tublues of the kidney. A quantitative immunological determination was made from the urine of 30 normal rats.