人肾中Tamm-Horsfall黏蛋白的免疫荧光定位
Immunofluorescent localization of Tamm-Horsfall mucoprotein in human kidney.
作者信息
McKenzie J K, McQueen E G
出版信息
J Clin Pathol. 1969 May;22(3):334-9. doi: 10.1136/jcp.22.3.334.
Abstract
A fluorescein-labelled antiserum to human Tamm-Horsfall mucoprotein applied to frozen human kidney sections gave strong specific labelling, mainly of cells of tubules in the outer medulla. By comparison with adjacent serial sections stained for alkaline phosphatase and succinic dehydrogenase, it is suggested that material reacting immunologically as Tamm-Horsfall muco-protein is found particularly in the cells of the ascending limb of the loop of Henle and the macula densa segment of the distal tubule.
摘要
将一种荧光素标记的抗人Tamm-Horsfall粘蛋白抗血清应用于冷冻的人肾切片，可产生强烈的特异性标记，主要在外髓质的肾小管细胞中。通过与用碱性磷酸酶和琥珀酸脱氢酶染色的相邻连续切片进行比较，表明免疫反应性与Tamm-Horsfall粘蛋白相同的物质特别存在于亨氏袢升支和远端小管致密斑段的细胞中。
Zotero 插件