Korosteleva T A, Kliucharev B V, Belokhvostova A T
Vopr Onkol. 1976;22(11):95-8.
Antigen containing the tryptophan metabolite -- 3-oxyanthranilic acid-(3-OAA-antigen) was determined by agarose precipitation method, using specific immune rabbit sera in 85 patients, admitted with the primary diagnosis of renal tumor. Among 85 patients 3-OAA-antigen was found in blood sera in 62 patients. Among 23 patients in whom 3-OAA-antigen was not revealed in 20 -- the diagnosis of renal tumor failed to be supported. The authors conclude, that it is possible to use the reaction of 3-OAA-antigen detection for establishing the diagnosis of tumors of the kidneys.
采用琼脂糖沉淀法，使用特异性免疫兔血清，对85例初步诊断为肾肿瘤的患者检测含色氨酸代谢产物——3 - 氧代邻氨基苯甲酸的抗原（3 - OAA - 抗原）。85例患者中，62例血清中发现有3 - OAA - 抗原。23例未检测到3 - OAA - 抗原的患者中，20例无法支持肾肿瘤的诊断。作者得出结论，3 - OAA - 抗原检测反应可用于肾肿瘤的诊断。
