Spevak P J, Mandell V S, Colan S D, Van Der Velde M E, Jonas R A, Lock J E, Sanders S P
Department of Pediatric Cardiology, Children's Hospital, Boston, Massachusetts.
Echocardiography. 1993 Nov;10(6):573-81. doi: 10.1111/j.1540-8175.1993.tb00073.x.
The purpose of this study was to compare Doppler color flow mapping with angiography and surgical observation for detection of multiple ventricular septal defects (VSDs). Only patients with elevated pulmonary ventricular pressure were included. Among 137 patients with VSDs, 38 multiple defects were identified in 25 patients echocardiographically, 34 multiple defects in 24 patients angiographically, and 21 multiple defects in 17 patients surgically. Using surgical observation as the reference standard, the sensitivity of echocardiography for identifying patients with multiple VSDs was 17 of 17 (100%) and for angiography 15 of 17 (88%). The sensitivity of echocardiography for identifying all multiple VSDs seen at operation was 19 of 21 (90%) and of angiography was also 19 of 21 (90%). In many patients, use of both techniques may no longer be necessary.
本研究的目的是比较彩色多普勒血流图与血管造影术及手术观察在检测多发性室间隔缺损（VSD）方面的效果。仅纳入了肺动脉压升高的患者。在137例VSD患者中，超声心动图检查发现25例患者存在38处多发性缺损，血管造影检查发现24例患者存在34处多发性缺损，手术发现17例患者存在21处多发性缺损。以手术观察作为参考标准，超声心动图识别多发性VSD患者的敏感性为17/17（100%），血管造影为15/17（88%）。超声心动图识别手术中所见所有多发性VSD的敏感性为19/21（90%），血管造影的敏感性同样为19/21（90%）。在许多患者中，可能不再需要同时使用这两种技术。
