Tzardis P J, Gruessner R W, Matas A J, Payne W D, Dunn D L, Sutherland D E, Najarian J S
Department of Surgery, University of Minnesota, Minneapolis.
Clin Transplant. 1990 Apr;4(2):108-11.
Eight patients with end-stage renal failure due to Wegener's granulomatosis underwent renal transplantation at the University of Minnesota. Seven patients were alive with a functioning graft 40 to 128 months posttransplant (mean follow-up: 91 months). One patient died 126 months posttransplant with a well-functioning graft. Posttransplant immunosuppression controlled primary disease in all but 1 patient, who presented with perisinusitis. Recurrent disease was not noted in any of the transplanted organs. We conclude that transplantation is an excellent treatment for renal failure secondary to Wegener's disease.
8例因韦格纳肉芽肿导致终末期肾衰竭的患者在明尼苏达大学接受了肾移植。7例患者移植后40至128个月移植肾仍存活且功能良好（平均随访时间：91个月）。1例患者在移植后126个月死亡，但其移植肾功能良好。除1例出现鼻窦周围炎的患者外，移植后的免疫抑制控制了所有患者的原发性疾病。在任何移植器官中均未发现疾病复发。我们得出结论，对于韦格纳病继发的肾衰竭，移植是一种极佳的治疗方法。
