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[利用条件反射系统对犬长期记忆与短期记忆之间相互关系的药理学分析]

[Pharmakologic analysis of the interrelationship between long-term and short-term memory in dogs with systems of conditioned reflexes].

作者信息

Selivanova A T

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1976 Nov-Dec;26(6):1222-30.

PMID:1014894
Abstract

It has been shown in experiments on dogs with elaborated integrated systems of conditioned reflexes (by Kupalov method) and choice reactions (by Hunter method); that the physiological mechanisms of short-term and long-term memory are not strictly isolated; they include some common biochemical structures and are interrelated. The action of amizyl or armin on the cholinoreceptors disturbs the short-term memory and some elements of the long-term conditioned memory: the duration of retention of traces from conditioned and unconditioned alimentary stimuli is reduced; regulation of the course of stabilized conditioned stereotypes is disturbed; differentiation and use of previous experience (extraction of data from long-term memory) are impeded.

摘要

在对狗进行的实验中已经表明,这些实验采用了精细的条件反射综合系统(库帕洛夫方法)和选择反应(亨特方法);短期和长期记忆的生理机制并非严格隔离;它们包括一些共同的生化结构且相互关联。阿米齐尔或阿明对胆碱能受体的作用会干扰短期记忆以及长期条件记忆的一些要素:条件性和非条件性食物刺激痕迹的保留时长缩短;稳定的条件反射模式进程的调节受到干扰;先前经验的区分和运用(从长期记忆中提取数据)受到阻碍。

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