Martinez J E, Beck J R, Allsbrook W C, Pantazis C G
Department of Pathology, Medical College of Georgia, Augusta 30912.
Clin Lab Sci. 1990 May-Jun;3(3):180-3.
Flow cytometric DNA analysis, including principles, techniques, and applications, is reviewed. Flow cytometry, a relatively recently developed technology, is being increasingly used in the diagnosis and treatment of a wide variety of benign and malignant diseases. Current major applications include phenotypic analysis of cells, cell sorting, and DNA analysis. DNA analysis by flow cytometry is rapid, reliable, and reproducible. Flow cytometric DNA analysis offers a quick, reliable method of analyzing cellular DNA content capable of identifying cell populations with abnormalities in total DNA content.
本文综述了流式细胞术DNA分析，包括其原理、技术及应用。流式细胞术是一项相对较新开发的技术，正越来越多地用于各种良性和恶性疾病的诊断与治疗。目前的主要应用包括细胞表型分析、细胞分选及DNA分析。通过流式细胞术进行DNA分析快速、可靠且可重复。流式细胞术DNA分析提供了一种快速、可靠的方法来分析细胞DNA含量，能够识别总DNA含量异常的细胞群体。
