Whalley D, McKenna S P
Galen Research, Manchester, England.
Pharmacoeconomics. 1995 Oct;8(4):305-15. doi: 10.2165/00019053-199508040-00005.
One-fifth of all disability is caused by psychiatric morbidity, with depression and anxiety the most common conditions. Despite this, and the wide range of pharmaceutical treatments available, few quality-of-life studies have been conducted with depressed or anxious patients. Most studies focus on symptoms and adverse effects, rather than on the impact of these on the patient. Where health status is assessed, inappropriate generic measures have been used. Recently, a depression-specific measure of quality of life, the Quality of Life in Depression Scale, has been developed and is starting to be used in clinical trials. No equivalent measure for anxiety is available. Given the range and rapid increase in the number of treatments available for depression and anxiety, and issues of compliance and individual response to treatment, much more attention must be given to quality of life in these conditions.
所有残疾中有五分之一是由精神疾病导致的,其中抑郁症和焦虑症最为常见。尽管如此,且有各种各样的药物治疗方法,但针对抑郁症或焦虑症患者开展的生活质量研究却很少。大多数研究关注的是症状和不良反应,而非这些对患者的影响。在评估健康状况时,使用的是不恰当的通用测量方法。最近,一种专门针对抑郁症的生活质量测量工具——抑郁生活质量量表已经开发出来,并开始在临床试验中使用。目前还没有针对焦虑症的等效测量工具。鉴于治疗抑郁症和焦虑症的方法种类繁多且数量迅速增加,以及依从性和个体对治疗的反应等问题,必须更加关注这些病症患者的生活质量。