Price J F, Cogswell J J, Joseph M C, Cochrane G M
Arch Dis Child. 1976 Dec;51(12):912-7. doi: 10.1136/adc.51.12.912.
Forty-two children with eczema were studied for exercise-induced asthma (EIA), skin sensitivity to prick testing, blood eosinophil count, and immunoglobulins. 29 had a fall in peak expiratory flow rate after exercise greater than 20% and of these, 23 had symptoms of wheezing. 13 of the eczematous children showed a fall of less than 20%. The children with EIA showed greater cutaneous sensitivity (p less than 0.001) and a higher total serum IgE (p less than 0.025). 3 of the group with a fall of less than 20% had allergic rhinitis with skin sensitivity to grass pollen. The remaining 10 had no clinical evidence of allergic disease, other than eczema and skin sensitivity, and total IgE fell within the normal range. It is suggested that in a proportion of chilren with eczema there is little evidence of reaginic allergy.
对42名患有湿疹的儿童进行了运动诱发性哮喘（EIA）、皮肤点刺试验敏感性、血液嗜酸性粒细胞计数及免疫球蛋白的研究。29名儿童运动后呼气峰值流速下降超过20%，其中23名有喘息症状。13名湿疹儿童的呼气峰值流速下降小于20%。患有EIA的儿童表现出更高的皮肤敏感性（p<0.001）和更高的血清总IgE（p<0.025）。呼气峰值流速下降小于20%的儿童组中有3名患有对草花粉皮肤敏感的过敏性鼻炎。其余10名儿童除湿疹和皮肤敏感外，没有过敏性疾病的临床证据，且总IgE在正常范围内。提示一部分患有湿疹的儿童几乎没有反应素性过敏的证据。
