Day R E, Insley J
Arch Dis Child. 1976 Dec;51(12):935-8. doi: 10.1136/adc.51.12.935.
Twenty-five out of 205 (i.e. 12%) babies born to diabetic mothers in the Birmingham Maternity Hospital in the period 1969-1974 were malformed as against 6% in a control group. The incidence was highest in the group where mothers were on insulin at the time of conception (17 out of 117, i.e. 15%). No correlation was observed between major malformation in this group and age of onset or duration of the diabetes, progressive vascular complications, maternal age, or parity. Cardiovascular malformations were over-represented.
1969年至1974年期间，在伯明翰妇产医院出生的205名糖尿病母亲所生婴儿中有25名（即12%）出现畸形，而对照组的这一比例为6%。在母亲受孕时使用胰岛素的组别中，发病率最高（117名中有17名，即15%）。未观察到该组中的严重畸形与糖尿病的发病年龄或病程、进行性血管并发症、母亲年龄或产次之间存在相关性。心血管畸形的比例过高。
