Orsi A, Parri F
Ann Sclavo. 1976 Mar-Apr;18(2):223-32.
The validity of the direct antimicrobial disc susceptibility test has been compared with the same test carried out on bacterial strains isolated from clinical materials obtained from the respiratory tract. The experimental evidence so far obtained raises some doubts concerning the reiliability of the direct test. The use of the latter seems to be reccomended in urgent cases only considering that either with multimicrobic or monomicrobic material the results obtained are partial and slightly reproducible. The conclusion is that, in order to obtain an accurate picture of the sensitivity to the various antibiotics, the direct test should be followed always with the antimicrobial disc susceptibility test carried out with isolated strains.
已将直接抗菌药敏试验的有效性与对从呼吸道获取的临床材料中分离出的细菌菌株进行的相同试验进行了比较。目前获得的实验证据对直接试验的可靠性提出了一些疑问。仅在紧急情况下才建议使用后者,因为无论是对于混合微生物材料还是单一微生物材料,所获得的结果都是不完整的且重现性较差。结论是,为了准确了解对各种抗生素的敏感性,直接试验之后应始终进行对分离菌株的抗菌药敏试验。