Hörnquist J O, Wikby A, Stenström U, Andersson P O, Akerlind I
Research Unit of the County of Jämtland, Mid Sweden University, Ostersund.
Pharmacoeconomics. 1995;8 Suppl 1:12-6. doi: 10.2165/00019053-199500081-00004.
In this review, an attempt was made to describe how non-insulin-dependent diabetes mellitus (NIDDM, type II diabetes) affects the life of the ill person. Patients are affected by and cope with this complex disease in different ways, depending on its severity and complications. Influences on well-being therefore also vary--from none to major deterioration. A substantial proportion of patients are primarily affected with fatigue, anxiety, and depression. Deteriorations in cognitive function have also been documented, although diverging evidence exists. Some negative social circumstances have also been noted. Social support, particularly specific support, appears to be helpful, although self-efficacy and health practices seem to be as important. Resistance to compliance with diabetes regimens together with reactions to the demands for increased levels of physical activity are often seen. Systematic focused studies examining how patients and significant others perceive the impact of the disease in retrospect are still awaited. There is a great need for more research on type II diabetes; broad prospective longitudinal follow-up studies monitoring natural disease progression, as well as examining the predictive significance of quality of life, would be welcome.
在本综述中,我们试图描述非胰岛素依赖型糖尿病(NIDDM,II型糖尿病)如何影响患者的生活。患者受这种复杂疾病的影响并以不同方式应对,这取决于疾病的严重程度和并发症。因此,对幸福感的影响也各不相同——从无影响到严重恶化。相当一部分患者主要受到疲劳、焦虑和抑郁的影响。虽然存在不同的证据,但认知功能的恶化也有记录。还注意到一些负面的社会情况。社会支持,特别是特定的支持,似乎是有帮助的,尽管自我效能感和健康行为似乎同样重要。经常可以看到患者对糖尿病治疗方案的依从性存在抵触,以及对增加体力活动要求的反应。仍有待进行系统的重点研究,以回顾性地考察患者及重要他人如何看待该疾病的影响。对II型糖尿病的研究非常需要进一步加强;开展广泛的前瞻性纵向随访研究,监测疾病的自然进展,并考察生活质量的预测意义,将是很受欢迎的。