Wright J F, Lazarus A H, Freedman J
Department of Immunohematology, University of Toronto, Canada.
Transfus Sci. 1995 Dec;16(4):333-41. doi: 10.1016/0955-3886(95)00044-5.
Flow cytometric analysis of blood leukocytes is currently used for both routine clinical measurements as well as for cutting edge research applications. This technology has enabled rapid and accurate determination of leukocyte antigens and quantitative analysis of leukocyte subsets, tests of leukocyte function, determination of the presence of antineutrophil and antilymphocyte antibodies in plasma and on cells, measurement of CD34+ hematpoietic stem cells in peripheral blood and bone marrow samples, measurement of apoptosis, and detection of virus-infected leukocytes. This review will focus on the use of the flow cytometer for investigations of blood leukocytes in transfusion medicine.
血液白细胞的流式细胞术分析目前既用于常规临床检测，也用于前沿研究应用。这项技术能够快速、准确地测定白细胞抗原，对白细胞亚群进行定量分析，检测白细胞功能，测定血浆和细胞中抗中性粒细胞和抗淋巴细胞抗体的存在，测量外周血和骨髓样本中的CD34+造血干细胞，测量细胞凋亡，并检测病毒感染的白细胞。本综述将重点关注流式细胞仪在输血医学中对血液白细胞进行研究的应用。
