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影响心肌和骨骼肌肾上腺素能受体的药物作用下葡萄糖淀粉酶活性的变化。

Changes in glucoamylase activity under the influence of drugs affecting the adrenergic receptors in myocardium and skeletal muscle.

作者信息

Wilczek J

出版信息

Arch Immunol Ther Exp (Warsz). 1976;24(6):837-43.

PMID:1015990
Abstract

The activity of neutral glucoamylase and alpha-amylase were determined in the myocardium and skeletal muscle after in vivo pharmacologic stimulation of adrenergic receptors. The activity changes of these enzymes were found to not always occur parallelly. The activity of both these enzymes is decreased under beta-agonistic influence of isoprenaline, adrenaline, as well as under the influence of acetylcholine. On the other hand, alpha-agonistic function of phenylephrine mainly results in the increase of neutral glucoamylase activity. Similar effects are obtained by suprarenal ligation. The above pharmacological effects did not appear when the said pharmacologic drugs were added to incubated muscle extracts.

摘要

在体内对肾上腺素能受体进行药理刺激后,测定了心肌和骨骼肌中中性葡糖淀粉酶和α-淀粉酶的活性。发现这些酶的活性变化并非总是平行发生。在异丙肾上腺素、肾上腺素的β-激动作用以及乙酰胆碱的作用下,这两种酶的活性均降低。另一方面,去氧肾上腺素的α-激动功能主要导致中性葡糖淀粉酶活性增加。肾上腺结扎也可获得类似效果。当将上述药理药物添加到孵育的肌肉提取物中时,未出现上述药理作用。

相似文献

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Changes in glucoamylase activity under the influence of drugs affecting the adrenergic receptors in myocardium and skeletal muscle.影响心肌和骨骼肌肾上腺素能受体的药物作用下葡萄糖淀粉酶活性的变化。
Arch Immunol Ther Exp (Warsz). 1976;24(6):837-43.
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引用本文的文献

1
alpha- and beta-adrenergic influences on metabolism in heart and skeletal muscle.α和β肾上腺素能对心脏和骨骼肌代谢的影响。
Vet Res Commun. 1983 Dec;7(1-4):369-75. doi: 10.1007/BF02228647.