Boujoukos A J, Martich G D
Department of Anesthesia and Critical Care Medicine, University of Pittsburgh, PA, USA.
J Intensive Care Med. 1996 Jan-Feb;11(1):23-36. doi: 10.1177/088506669601100105.
A ventricular assist device (VAD) is a heterotopic mechanical pump that augments or replaces the output of a failing ventricle. In the past decade, investigation and use of these devices has greatly improved our understanding of their potential roles and limitations. Successful univentricular and biventricular support has allowed for myocardial recovery and survival in several settings of intractable cardiogenic shock. The development of long-term VADs has allowed for successful bridging of patients to heart transplantation, and it has laid the groundwork for a permanent implantable replacement ventricle. In this review, we address indications, complications, management, and results of mechanical support in postcardiotomy, bridge to recovery, and bridge to transplantation settings. The tools to achieve ventricular support in the United States, and the VADs themselves, are described, with emphasis on unique features, indications, and limitations.
心室辅助装置（VAD）是一种异位机械泵，可增强或替代功能衰竭心室的输出。在过去十年中，对这些装置的研究和使用极大地增进了我们对其潜在作用和局限性的理解。成功的单心室和双心室支持已使心肌在几种难治性心源性休克情况下得以恢复并存活。长期VAD的发展已使患者成功过渡到心脏移植，并且为永久性可植入替代心室奠定了基础。在本综述中，我们阐述了心脏切开术后、过渡到恢复以及过渡到移植情况下机械支持的适应证、并发症、管理和结果。描述了在美国实现心室支持的工具以及VAD本身，重点介绍了其独特特征、适应证和局限性。
