Bobbio P, Roncoroni L, Salcuni P, Violi V
Ateneo Parmense Acta Biomed. 1976 Mar-Apr;47(2):125-38.
110 of 126 patients treated with Halsted mastectomy and postoperative loco-regional radiotherapy, during period 1961-1969 have been controlled. Overall 5 years survival resulted as following: Columbia Clinical Classification stage A 90,6%, stage B 66,6%, stage C 28,5%, stage D 33,3%; 10 years survival in patients operated on in the period 1961-64 was: stage A 69,2%, stage B 53,3%, stage C 40%, stage D 0%. On the basis of the satisfing results obtained the authors conclude that it appears by now unjustified to modify this method in treating stage A and B breast cancer either utilizing less extended resections, or renoncing to the postoperative irradiation.
在1961年至1969年期间，接受哈尔斯特德乳房切除术及术后局部区域放疗的126例患者中有110例得到了随访。总体5年生存率如下：哥伦比亚临床分期A期为90.6%，B期为66.6%，C期为28.5%，D期为33.3%；1961年至1964年接受手术的患者10年生存率为：A期69.2%，B期53.3%，C期40%，D期0%。基于所获得的令人满意的结果，作者得出结论：目前看来，无论是采用范围较小的切除术，还是放弃术后放疗，对A期和B期乳腺癌治疗方法进行修改都是不合理的。
