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[不同治疗方式对原发性可手术乳腺癌的疗效评估(作者译)]

[Evaluation of efficacy of different modes of treatment in primary operable breast cancer (author's transl)].

作者信息

Baschenowa A, Barwitenko P

出版信息

Arch Geschwulstforsch. 1977;47(4):355-60.

PMID:921490
Abstract

In the 10 year-period 1960--1969, 888 patients with primary operable mammary cancer were treated in the P. A. Herzen Oncological Institute. Survival rates after 5 years were analyzed for 888 patients, 10 year rates for 410 patients. Irrespective of the size of the primary tumor, 82.3% of those without regional lymphnode metastases survived 5 years whereas only 44.7 percent of patients with regional lymphnode metastases were cured for more than 5 years. The 5-year survival rate was 84.2 percent for surgical treatment only, 58.6--78.9% for combined treatment (radical mastectomy plus irradiation) and 51.5--31.4% for so-called complex treatment (surgery + irradiation + hormonal or cytostatic treatment). It is concluded that breast cancer is curable if detected and treated in an early stage but that results of treatment in advanced stages are unsatisfactory also if all contemporary available methods of therapy are applied.

摘要

在1960年至1969年的10年期间,888例原发性可手术乳腺癌患者在帕维尔·阿列克谢耶维奇·赫岑肿瘤研究所接受了治疗。对888例患者进行了5年生存率分析,对410例患者进行了10年生存率分析。无论原发肿瘤大小如何,无区域淋巴结转移的患者中有82.3%存活了5年,而有区域淋巴结转移的患者中只有44.7%的患者存活超过5年。单纯手术治疗的5年生存率为84.2%,综合治疗(根治性乳房切除术加放疗)的5年生存率为58.6% - 78.9%,所谓的综合治疗(手术 + 放疗 + 激素或细胞抑制治疗)的5年生存率为51.5% - 31.4%。得出的结论是,如果在早期发现并治疗,乳腺癌是可以治愈的,但即使应用了所有当代可用的治疗方法,晚期治疗结果也不尽人意。

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