Andreasen A H, Mouridsen H T, Andersen K W, Lynge E, Madsen M, Olesen K P
Danish Cancer Society.
Stud Health Technol Inform. 1994;14:27-38.
The trend in the prognosis for female breast cancer patients was investigated by comparing Kaplan-Meier survival curves of different patient cohorts diagnosed during the period 1948-87. The study is based on 71,448 patients from the Danish Cancer Registry. The cohorts were defined by age at diagnosis, year of diagnosis, and residential area. The survival time from diagnosis nearly doubled from 1948-57 to 1978-87, the most important improvement taking place after 1978. Patients diagnosed in 1948-77 in the Copenhagen area had a far better prognosis than patients diagnosed during this period in other parts of Denmark. For patients diagnosed in 1978-87 the prognosis, however, reached an equal level in all parts of the country. Thus, it is reasonable to assume that the national programme introduced in 1977 by the Danish Breast Cancer Cooperative Group (DBCG) has played an important role and not only brought about therapeutic improvements in breast cancer treatment in Denmark, but also ensured equity in the outcome on a national scale.
通过比较1948年至1987年期间确诊的不同患者队列的Kaplan-Meier生存曲线，研究了女性乳腺癌患者的预后趋势。该研究基于丹麦癌症登记处的71448名患者。这些队列根据诊断时的年龄、诊断年份和居住地区进行定义。从诊断到生存的时间从1948年至1957年到1978年至1987年几乎翻了一番，最重要的改善发生在1978年之后。1948年至1977年在哥本哈根地区确诊的患者预后比同期在丹麦其他地区确诊的患者好得多。然而，对于1978年至1987年确诊的患者，全国各地区的预后达到了相同水平。因此，可以合理地假设，丹麦乳腺癌合作组（DBCG）1977年推出的国家计划发挥了重要作用，不仅在丹麦乳腺癌治疗方面带来了治疗改善，而且在全国范围内确保了治疗结果的公平性。
