Linck G, Petrovic A, Stoeckel M E, Porte A
Bull Assoc Anat (Nancy). 1976 Mar;60(168):201-9.
Classical histological descriptions of the modifications of the mouse pubic symphysis (PS) during pregnancy did not take sufficient account of its structural heterogeneity. Precise morphological study of the PS, in adult male and virgin female mice, was carried out under light and electronic microscopy. Our observations on pregnant females are still imcomplete. Two regions of the PS should be distinguished according to their structure and evolution during pregnancy. The cranial region shows diarthrodial articular characteristics. This region disappears in the female during the first pregnancy and is not reconstituted after parturition. The caudal region comprises two types of cells in the female : typical chondrocytes and a peculiar cell-type whose function has yet to be defined. The latter seems to be responsible for the loose structure of the symphyseal cartilage and to contribute to the development of pseudocavities in the ligament in the final days of pregnancy. It is possible that such cells may be stimulated by relaxin and may secrete a hydrophilic factor such as hyaluronic acid.
关于小鼠耻骨联合（PS）在妊娠期间变化的经典组织学描述并未充分考虑其结构的异质性。在成年雄性和未孕雌性小鼠中，对耻骨联合进行了光镜和电镜下的精确形态学研究。我们对妊娠雌性小鼠的观察仍不完整。耻骨联合的两个区域应根据其在妊娠期间的结构和演变加以区分。头侧区域表现出动关节的关节特征。该区域在雌性小鼠首次妊娠期间消失，产后不会重建。尾侧区域在雌性小鼠中包含两种细胞类型：典型的软骨细胞和一种功能尚未明确的特殊细胞类型。后者似乎导致了耻骨联合软骨的疏松结构，并在妊娠最后几天促使韧带中出现假腔。这些细胞可能受松弛素刺激，并可能分泌一种亲水性因子，如透明质酸。
