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长期高碳酸血症对大鼠血浆氨基酸的影响(作者译)

[Effects of long term hypercapnia on plasma amino acids in the rat (author's transl)].

作者信息

Bange C, Radziszewski E, Curé M, Guillerm R, Pérès G

出版信息

Bull Eur Physiopathol Respir. 1976 Jan-Feb;12(1):165-76.

PMID:1016769
Abstract

Rats have been placed for periods from two hours to 22 days in a chamber, the atmosphere of which was enriched in CO2 (FICO2: 0.10). The acute phase of hypercapnia induces multidirectional changes of many plasma amino acids. Some of these changes lessen or become of an opposite direction during the first days of exposure; most of them disappear when the hypercapnic acidosis is partly compensated. The variety of these reactions seems due to the fact that CO2 brings into play various mechanisms of synthesis, circulation and catabolism.

摘要

将大鼠置于一个舱室内两小时至22天,舱室内的二氧化碳浓度升高(FICO2:0.10)。高碳酸血症的急性期会引起多种血浆氨基酸的多向变化。其中一些变化在暴露的最初几天会减轻或变为相反方向;当高碳酸血症性酸中毒得到部分代偿时,大多数变化会消失。这些反应的多样性似乎是由于二氧化碳发挥了各种合成、循环和分解代谢机制。

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