Mansour A M
Department of Ophthalmology, American University of Beirut-Medical Center, Beirut, Lebanon.
Curr Opin Ophthalmol. 1997 Jun;8(3):55-8. doi: 10.1097/00055735-199706000-00010.
Cytomegalovirus (CMV) optic neuritis is a rapidly blinding disease. Untreated eyes have a final visual acuity of no light perception. Treated eyes maintain visual acuity of approximately 20/100. Relapse occurs often in subjects maintained on single-dose ganciclovir and is controlled by double-dose ganciclovir. Central visual field testing is indicated to detect indolent cases of optic neuritis, because relapse can be silent with stable visual acuity and fundus appearance. Survival of patients with CMV optic neuritis is comparable to that of a matched group having CMV retinitis alone. Early recognition and therapy of CMV papillitis protect against irreversible visual loss. CMV papillitis does not carry a worse prognosis for survival than CMV retinitis alone.
巨细胞病毒（CMV）视神经炎是一种迅速导致失明的疾病。未经治疗的眼睛最终视力为无光感。接受治疗的眼睛可维持约20/100的视力。接受单剂量更昔洛韦治疗的患者经常复发，而双剂量更昔洛韦可控制复发。建议进行中心视野检查以检测视神经炎的隐匿性病例，因为在视力和眼底外观稳定的情况下，复发可能没有症状。CMV视神经炎患者的生存率与仅患有CMV视网膜炎的匹配组相当。CMV视乳头炎的早期识别和治疗可防止不可逆转的视力丧失。CMV视乳头炎的生存预后并不比仅患有CMV视网膜炎更差。
