Pokorski R J
Cologne Life Reinsurance Company, Stamford, CT 06905, USA.
J Insur Med. 1997;29(2):101-6.
Long-term survival of patients with multiple sclerosis is not well characterized because this disorder is relatively uncommon and subjects must be followed for decades after onset of symptoms. This paper reports comparative mortality experience of the world's largest series on an unselected cohort with multiple sclerosis.
Excess mortality varied with age, gender, duration since onset and diagnosis, calender year of onset, and clinical severity.
Compared to the general population in Denmark, patients with multiple sclerosis had less favorable survival experience during long-term follow-up.
由于多发性硬化症相对不常见，且患者在症状出现后必须随访数十年，因此对该疾病患者的长期生存情况尚无充分描述。本文报告了世界上最大规模的未选择多发性硬化症队列的比较死亡率情况。
超额死亡率随年龄、性别、起病和诊断后的病程、起病年份以及临床严重程度而变化。
与丹麦普通人群相比，多发性硬化症患者在长期随访期间的生存情况较差。
