Jansen J A, van der Waerden J P, Wolke J G
Department of Oral Function and Prosthetic Dentistry, Dental School, University of Nijmegen, The Netherlands.
J Appl Biomater. 1993 Fall;4(3):213-9. doi: 10.1002/jab.770040302.
The aim of this study was to investigate the bone response to three different types of titanium (Ti) alloys and hydroxyapatite (HA) coated titanium alloy by histological and histomorphometrical analysis. Therefore, implants made of these materials were inserted into the tibia of rabbits. Implantation times were 6 and 16 weeks. The histological evaluation included measurement of the amount of bone apposition and analysis of the bone reaction and interface characteristics around the implants. The results demonstrated no marked differences in bony reaction to the different implant materials. In addition, the HA coatings showed loss of thickness.
本研究的目的是通过组织学和组织形态计量学分析，研究三种不同类型的钛（Ti）合金以及羟基磷灰石（HA）涂层钛合金的骨反应。因此，将由这些材料制成的植入物植入兔胫骨。植入时间为6周和16周。组织学评估包括测量骨附着量以及分析植入物周围的骨反应和界面特征。结果表明，不同植入材料的骨反应无明显差异。此外，HA涂层显示出厚度损失。
