Watsky M S, Lynfield Y L
Cutis. 1976 Feb;17(2):361-3.
Because griseofulvin is one of the safest systemic medications, its side effects are often forgotten. This paper serves as a reminder that griseofulvin can precipitate or exacerbate lupus erythematosus. Two patients are described: one had a photosensitivity reaction to griseofulvin which precipitated discoid LE skin lesions, without any previous evidence of LE. The other, who had known systemic LE, developed a systemic reaction, consisting of fever and malasise.
由于灰黄霉素是最安全的全身用药之一，其副作用常常被遗忘。本文旨在提醒人们灰黄霉素可诱发或加重红斑狼疮。文中描述了两名患者：一名患者对灰黄霉素出现光敏反应，诱发了盘状红斑狼疮皮肤损害，此前并无红斑狼疮的任何证据。另一名患者已知患有系统性红斑狼疮，出现了包括发热和不适在内的全身反应。
