西咪替丁相关的皮肤红斑狼疮病情加重。
Cimetidine-associated exacerbation of cutaneous lupus erythematosus.
作者信息
Davidson B L, Gilliam J N, Lipsky P E
出版信息
Arch Intern Med. 1982 Jan;142(1):166-7.
PMID:7053721
Abstract
A patient with systemic lupus erythematosus (SLE) had new LE skin lesions develop following the initiation of cimetidine, a drug that is known to influence a variety of cellular functions. The temporal relationship between the onset of cutaneous LE with the ingestion of cimetidine is reported to alert others to the possibility that this H2 receptor antagonist may exacerbate cutaneous disease activity in patients with LE.
摘要
一名系统性红斑狼疮（SLE）患者在开始服用西咪替丁后出现了新的红斑狼疮皮肤病变，已知该药物会影响多种细胞功能。据报道，皮肤型红斑狼疮发作与西咪替丁摄入之间的时间关系，提醒其他人注意这种H2受体拮抗剂可能会加重红斑狼疮患者的皮肤疾病活动的可能性。
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